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Literature summary extracted from
- Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow (2009), Exp. Biol. Med., 234, 504-512.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.1 | DL-propargylglycine | irreversible inhibitor of CSE | Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.1 | L-cysteine + H2O | Rattus norvegicus | - |
sulfide + NH3 + pyruvate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.1 | Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.1 | L-cysteine + H2O | - |
Rattus norvegicus | sulfide + NH3 + pyruvate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.4.1.1 | CSE | - |
Rattus norvegicus |
| 4.4.1.1 | cystathionine-gamma-lyase | - |
Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.1 | pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.4.1.1 | metabolism | CSE is a key enzyme in the pathway of cystathionine metabolism to produce endogenous H2S | Rattus norvegicus |
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Release 2023.1 (January 2023)
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