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Literature summary extracted from

  • Martin, G.R.; McKnight, G.W.; Dicay, M.S.; Coffin, C.S.; Ferraz, J.G.; Wallace, J.L.
    Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract (2010), Dig. Liver Dis., 42, 103-109.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 DL-propargylglycine irreversible inhibitor of CSE Homo sapiens
4.4.1.1 DL-propargylglycine irreversible inhibitor of CSE Mus musculus
4.4.1.1 DL-propargylglycine irreversible inhibitor of CSE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Homo sapiens
-
-
-
4.4.1.1 Mus musculus
-
-
-
4.4.1.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.1 brain
-
 Mus musculus
-
4.4.1.1 brain
-
 Rattus norvegicus
-
4.4.1.1 colon
-
 Mus musculus
-
4.4.1.1 colon
-
 Homo sapiens
-
4.4.1.1 colon
-
 Rattus norvegicus
-
4.4.1.1 duodenum
-
 Mus musculus
-
4.4.1.1 duodenum
-
 Rattus norvegicus
-
4.4.1.1 gastrointestinal tract
-
 Mus musculus
-
4.4.1.1 gastrointestinal tract
-
 Rattus norvegicus
-
4.4.1.1 ileum
-
 Mus musculus
-
4.4.1.1 ileum
-
 Rattus norvegicus
-
4.4.1.1 jejunum
-
 Mus musculus
-
4.4.1.1 jejunum
-
 Rattus norvegicus
-
4.4.1.1 liver
-
 Mus musculus
-
4.4.1.1 liver
-
 Homo sapiens
-
4.4.1.1 liver
-
 Rattus norvegicus
-
4.4.1.1 lung
-
 Mus musculus
-
4.4.1.1 lung
-
 Rattus norvegicus
-
4.4.1.1 stomach
-
 Mus musculus
-
4.4.1.1 stomach
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cysteine + H2O
-
 Mus musculus sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Homo sapiens sulfide + NH3 + pyruvate
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Rattus norvegicus sulfide + NH3 + pyruvate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 CSE
-
 Mus musculus
4.4.1.1 CSE
-
 Homo sapiens
4.4.1.1 CSE
-
 Rattus norvegicus
4.4.1.1 cystathionine-gamma-lyase
-
 Mus musculus
4.4.1.1 cystathionine-gamma-lyase
-
 Homo sapiens
4.4.1.1 cystathionine-gamma-lyase
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.1 pyridoxal 5'-phosphate
-
 Mus musculus
4.4.1.1 pyridoxal 5'-phosphate
-
 Homo sapiens
4.4.1.1 pyridoxal 5'-phosphate
-
 Rattus norvegicus