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Literature summary extracted from

  • Lee, K.S.; Kim, B.Y.; Choo, Y.M.; Yoon, H.J.; Kang, P.D.; Woo, S.D.; Sohn, H.D.; Roh, J.Y.; Gui, Z.Z.; Je, Y.H.; Jin, B.R.
    Expression profile of cathepsin B in the fat body of Bombyx mori during metamorphosis (2009), Comp. Biochem. Physiol. B, 154, 188-194.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.1 CatB DNA and amino acid sequence determination and analysis, recombinant expression in Spodoptera frugiperda cell line Sf9 using the baculovirus expression vector system with the Autographa californica nucleopolyhedrovirus Bombyx mori

Protein Variants

EC Number Protein Variants Comment Organism
3.4.22.1 additional information BmCatB RNAi treatment results in an arrest of the larval-pupal transformation. RNAi-mediated BmCatB knockdown sustains the expression of BmCatD during the larval-pupal transformation. On the other hand, when BmCatD is inhibited via RNAi, the expression of BmCatB is upregulated, overview Bombyx mori

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.1 lysosome
-
 Bombyx mori 5764
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.1 Bombyx mori
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.1 recombinant CatB from Sf9 insect cells Bombyx mori

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.1 fat body primarily, expression profile of cathepsin B in the fat body during metamorphosis, overview. CatB shows a high expression level during the larval-pupal transformation Bombyx mori
-

Synonyms

EC Number Synonyms Comment Organism
3.4.22.1 CatB
-
 Bombyx mori

Expression

EC Number Organism Comment Expression
3.4.22.1 Bombyx mori when BmCatD is inhibited via RNAi, the expression of BmCatB is upregulated up

General Information

EC Number General Information Comment Organism
3.4.22.1 malfunction BmCatB RNAi treatment results in an arrest of the larval-pupal transformation. RNAi-mediated BmCatB knockdown sustains the expression of BmCatD during the larval-pupal transformation. On the other hand, when BmCatD is inhibited via RNAi, the expression of BmCatB is upregulated Bombyx mori
3.4.22.1 physiological function BmCatB is involved in the programmed cell death of the fat body during metamorphosis, and CatB and CatD contribute to the metamorphosis Bombyx mori