EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.1 | additional information | serum-starvation increases cathepsin B-like activation in zebrafish follicles, not due to an increase in gene expression. No effects on cathepsin B activity by human chorionic gonadotropin and 17beta-estradiol | Danio rerio |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.1 | CA-074-Me | - |
Danio rerio | |
3.4.22.1 | additional information | No effects on cathepsin B activity by human chorionic gonadotropin and 17beta-estradiol | Danio rerio |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.22.1 | lysosome | - |
Danio rerio | 5764 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.1 | Danio rerio | Q6PH75 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.1 | vitelline gland | - |
Danio rerio | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.1 | N-benzyloxycarbonyl-Arg-Arg-4-methyl-7-amidocoumarin + H2O | - |
Danio rerio | N-benzyloxycarbonyl-Arg-Arg + 4-methyl-7-aminocoumarin | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.22.1 | 28 | - |
assay at | Danio rerio |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.22.1 | 6 | - |
assay at | Danio rerio |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.22.1 | physiological function | cathepsin B is involved in the regulation of apoptosis during serum-starvation in teleost follicles. Cathepsin B may play a role in the activation of the executioner caspase-3 | Danio rerio |