Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fried, L.F.; Duckworth, W.; Zhang, J.H.; OConnor, T.; Brophy, M.; Emanuele, N.; Huang, G.D.; McCullough, P.A.; Palevsky, P.M.; Seliger, S.; Warren, S.R.; Peduzzi, P.; Peduzzi, P.
    Design of combination angiotensin receptor blocker and angiotensin-converting enzyme inhibitor for treatment of diabetic nephropathy (VA NEPHRON-D) (2009), Clin. J. Am. Soc. Nephrol., 4, 361-368.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 lisinopril
-
 Homo sapiens
3.4.15.1 additional information both angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, e.g. losartan, can slow the progression of diabetic nephropathy, overview Homo sapiens
3.4.15.1 rampiril
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.15.1 angiotensin I + H2O Homo sapiens
-
 angiotensin II + His-Leu
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 kidney
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 angiotensin I + H2O
-
 Homo sapiens angiotensin II + His-Leu
-
 ?
3.4.15.1 angiotensin I + H2O i.e. DRVYIHPFHL Homo sapiens angiotensin II + His-Leu i.e. DRVYIHPF ?

Synonyms

EC Number Synonyms Comment Organism
3.4.15.1 ACE
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.15.1 malfunction both angiotensin-converting enzyme inhibitors and angiotensin receptor blockers can slow the progression of diabetic nephropathy, overview Homo sapiens