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Literature summary extracted from

  • Marcaccini, A.M.; Novaes, A.B.; Meschiari, C.A.; Souza, S.L.; Palioto, D.B.; Sorgi, C.A.; Faccioli, L.H.; Tanus-Santos, J.E.; Gerlach, R.F.
    Circulating matrix metalloproteinase-8 (MMP-8) and MMP-9 are increased in chronic periodontal disease and decrease after non-surgical periodontal therapy (2009), Clin. Chim. Acta, 409, 117-122.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.34 extracellular circulating MMP-8 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.34 Homo sapiens
-
-
-
3.4.24.35 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.34 plasma concentration of circulating MMP-8 is increased in periodontal disease patients compared to healthy controls, overview. Treatment reduces the level by by 35%, overview Homo sapiens
-
3.4.24.35 blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.34 Collagen + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.35 Gelatin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.34 Matrix metalloproteinase-8
-
 Homo sapiens
3.4.24.34 MMP-8
-
 Homo sapiens
3.4.24.35 matrix metalloproteinase-9
-
 Homo sapiens
3.4.24.35 MMP-9
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.24.34 30
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.34 7.5
-
 assay at Homo sapiens

Expression

EC Number Organism Comment Expression
3.4.24.35 Homo sapiens non-surgical periodontal therapy decreases blood plasma MMP-9 concentration by 39% down
3.4.24.35 Homo sapiens higher plasma MMP-9 concentrations are found in periodontal disease patients compared with healthy controls up