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Literature summary extracted from

  • Zhu, X.Y.; Liu, S.J.; Liu, Y.J.; Wang, S.; Ni, X.
    Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages (2010), Cell. Mol. Life Sci., 67, 1119-1132.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.1 43000
-
 SDS-PAGE Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.1 macrophage
-
 Mus musculus
-
4.4.1.1 RAW-264.7 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cystathionine + H2O
-
 Mus musculus L-homocysteine + pyruvate + NH3
-
 ?
4.4.1.1 L-cysteine + H2O
-
 Mus musculus sulfide + NH3 + pyruvate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 CSE
-
 Mus musculus
4.4.1.1 cysteine desulfhydrase
-
 Mus musculus

Expression

EC Number Organism Comment Expression
4.4.1.1 Mus musculus dexamethasone (0.001 mM) causes an about 85% decrease in CSE mRNA and 95% decrease in CSE protein levels, 1 mM NG-nitro-L-arginine methyl ester decreases lipopolysaccharide-induced CSE expression in macrophages down
4.4.1.1 Mus musculus 0.001 mg/ml lipopolysaccharide stimulates the CSE mRNA and protein levels 2.5fold, L-arginine (0.1-1 mM) dose-dependently enhances CSE mRNA and protein expression in lipopolysaccharide-treated primary macrophages up