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Literature summary extracted from

  • Waterworth, W.M.; Kozak, J.; Provost, C.M.; Bray, C.M.; Angelis, K.J.; West, C.E.
    DNA ligase 1 deficient plants display severe growth defects and delayed repair of both DNA single and double strand breaks (2009), BMC Plant Biol., 9, 79.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m Arabidopsis thaliana
-
 AMP + diphosphate + (deoxyribonucleotide)n+m
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.1 Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Arabidopsis thaliana AMP + diphosphate + (deoxyribonucleotide)n+m
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.5.1.1 DNA ligase I
-
 Arabidopsis thaliana
6.5.1.1 LigI
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
6.5.1.1 ATP
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
6.5.1.1 malfunction knockout mutants of lig1 are lethal. lig1-RNAi lines with reduced levels of LIG1 display slower repair of single strand breaks and also double strand breaks Arabidopsis thaliana
6.5.1.1 physiological function LIG1 is involved in repair of of single strand breaks and double strand breaks Arabidopsis thaliana