EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
7.1.1.2 | 3-azido-ubiquinone-2 | - |
Bos taurus | |
7.1.1.2 | 6-amino-4-(4-tert-butylphenethylamino)quinazoline | - |
Bos taurus | |
7.1.1.2 | 6-azido-4-(4-iodophenethylamino)quinazoline | the compound specifically binds to the 49000 Da and ND1 subunits with a frequency of about 4:1 | Bos taurus | |
7.1.1.2 | 6-azido-N-[2-(4-tert-butylphenyl)ethyl]-6,7-dihydroquinazolin-4-amine | - |
Bos taurus | |
7.1.1.2 | bullatacin | - |
Bos taurus | |
7.1.1.2 | fenpyroximate | - |
Bos taurus | |
7.1.1.2 | Piericidin A | - |
Bos taurus | |
7.1.1.2 | pyridabene | - |
Bos taurus | |
7.1.1.2 | rotenone | - |
Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
7.1.1.2 | mitochondrion | - |
Bos taurus | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.19 | Staphylococcus aureus | - |
- |
- |
7.1.1.2 | Bos taurus | P17694 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.19 | commercial preparation | - |
Staphylococcus aureus | - |
7.1.1.2 | heart | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.19 | 6-azido-4-(4-iodophenethylamino)quinazoline-labeled 49 kDa subunit of NADH-ubiquinone oxidoreductase + H2O | proteolytic mapping of the 49 kDa subunit with V8-protease, cleavage within the sequence region Asp41-Arg63: fragment A is predicted to be the peptide Thr25-Glu248, 224 amino acids, 26.0 kDa, which is further cleaved at Glu143 and give fragment B, Thr25-Glu143, 118 amino acids, overview | Staphylococcus aureus | ? | - |
? | |
7.1.1.2 | NADH + H+ + ubiquinone-1 | - |
Bos taurus | NAD+ + ubiquinol-1 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.19 | V8-protease | - |
Staphylococcus aureus |
7.1.1.2 | complex I | - |
Bos taurus |
7.1.1.2 | mitochondrial proton-pumping NADH-ubiquinone oxidoreductase | - |
Bos taurus |
7.1.1.2 | NADH-ubiquinone oxidoreductase | - |
Bos taurus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.21.19 | 37 | - |
assay at | Staphylococcus aureus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.19 | 7.8 | - |
assay at | Staphylococcus aureus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
7.1.1.2 | NADH | - |
Bos taurus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
7.1.1.2 | 0.0000023 | - |
temperature not specified in the publication, in 20 mM Tris-HCl, pH 7.4 | Bos taurus | 6-azido-N-[2-(4-tert-butylphenyl)ethyl]-6,7-dihydroquinazolin-4-amine | |
7.1.1.2 | 0.0000045 | - |
pH and temperature not specified in the publication | Bos taurus | 6-amino-4-(4-tert-butylphenethylamino)quinazoline |