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Literature summary extracted from

  • Kelley, M.; Vessey, D.A.
    Interaction of 2,4-dichlorophenoxyacetate (2,4-D) and 2,4,5-trichlorophenoxyacetate (2,4,5-T) with the acyl-CoA: amino acid N-acyltransferase enzymes of bovine liver mitochondria (1986), Biochem. Pharmacol., 35, 289-295.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.192 2,4,5-trichlorophenoxyacetyl-CoA competitive Bos taurus
2.3.1.192 2,4-dichlorophenoxyacetyl-CoA competitive Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.192 9
-
 glycine cosubstrate phenylacetyl-CoA, pH 8.0, 30°C Bos taurus
2.3.1.192 1000
-
 glycine cosubstrate 2,4-dichlorophenoxyacetyl-CoA pH 8.0, 30°C Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.192 mitochondrion
-
 Bos taurus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.192 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.192 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.192 2,4-dichlorophenoxyacetyl-CoA + glycine
-
 Bos taurus 2,4-dichlorophenoxyacetylglycine + CoA
-
 ?
2.3.1.192 additional information no substrate: 2,4,5-trichlorophenoxyacetyl-CoA Bos taurus ?
-
 ?
2.3.1.192 phenoxyacetyl-CoA + glycine overall rate of conjugation of the phenoxyherbicides are slow relative to the standard substrate phenylacetyl-CoA Bos taurus phenoxyacetylglycine + CoA
-
 ?
2.3.1.192 phenylacetyl-CoA + glycine
-
 Bos taurus phenylacetylglycine + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.192 phenylacetyltransferase
-
 Bos taurus