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Literature summary extracted from

  • Yu, B.; Xu, P.; Zhu, S.; Cai, X.; Wang, Y.; Li, L.; Li, F.; Liu, X.; Ma, C.
    Selective biodegradation of S and N heterocycles by a recombinant Rhodococcus erythropolis strain containing carbazole dioxygenase (2006), Appl. Environ. Microbiol., 72, 2235-2238.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
1.14.12.22 degradation expression of genes CarAacd in dibenzothiophene degrader Rhodococcus erythropolis results in a strain capable of efficiently degrading dibenzothiophene and carbazole simultaneously. About 37% of the carbazole present, 0.8% by weight, is removed after treatment for 24 h.The recombinant strain can also degrade various alkylated derivatives of carbazole and dibenzothiophene in FS4800 crude oil by just a one-step bioprocess Pseudomonas sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.12.22 expression of genes CarAacd in Rhodococcus erythropolis Pseudomonas sp.

Organism

EC Number Organism UniProt Comment Textmining
1.14.12.22 Pseudomonas sp.
-
-
-
1.14.12.22 Pseudomonas sp. CA10
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.12.22 carbazole + NAD(P)H + H+ + O2
-
Pseudomonas sp. 2'-aminobiphenyl-2,3-diol + NAD(P)+
-
?
1.14.12.22 carbazole + NAD(P)H + H+ + O2
-
Pseudomonas sp. CA10 2'-aminobiphenyl-2,3-diol + NAD(P)+
-
?
1.14.12.22 dibenzothiophene + NAD(P)H + H+ + O2
-
Pseudomonas sp. dibenzothiophene-5-oxide + NAD(P)+
-
?
1.14.12.22 dibenzothiophene + NAD(P)H + H+ + O2
-
Pseudomonas sp. CA10 dibenzothiophene-5-oxide + NAD(P)+
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.12.22 NAD(P)H
-
Pseudomonas sp.