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Literature summary extracted from

  • Yeum, K.J.; Orioli, M.; Regazzoni, L.; Carini, M.; Rasmussen, H.; Russell, R.M.; Aldini, G.
    Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humans (2010), Amino Acids, 38, 847-858.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.20 Homo sapiens Q96KN2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.13.20 blood
-
 Homo sapiens
-
3.4.13.20 urine
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.20 anserine + H2O
-
 Homo sapiens beta-Ala + Ntau-methyl-L-histidine
-
 ?
3.4.13.20 L-carnosine + H2O
-
 Homo sapiens beta-Ala + His
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.13.20 serum carnosinase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.13.20 37
-
 assay at Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.13.20 metabolism carnosine and anserine are mainly hydrolyzed by carnosinase, a low but significant amount is excreted in the urine. Carnosine reaches a steady state of very low concentration in serum, while anserine sustains higher concentrations than that of carnosine due to its greater stability vis-a-vis carnosinase after ingesting histidine-dipeptide rich diet Homo sapiens