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Literature summary extracted from
- The role of glyoxalase system in renal hypoxia (2010), Adv. Exp. Med. Biol., 662, 49-55.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 4.4.1.5 | expressed in Rattus norvegicus | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.5 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.5 | methylglyoxal + glutathione | - |
Homo sapiens | (R)-S-lactoylglutathione | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.4.1.5 | glyoxalase I | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.5 | glutathione | - |
Homo sapiens | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 4.4.1.5 | physiological function | glyoxalase I has renoprotective effects in renal hypoxia such as ischemia/reperfusion injury via a reduction in cytotoxic methylglyoxal level in tubular cell | Homo sapiens |
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Release 2023.1 (January 2023)
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