EC Number | Application | Comment | Organism |
---|---|---|---|
5.3.99.3 | medicine | MPGES-1 is an alternative therapeutic target in cancer cells expressing this enzyme | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
5.3.99.3 | microsome | - |
Homo sapiens | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | Prostaglandin H2 | Homo sapiens | - |
Prostaglandin E2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.3 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
5.3.99.3 | A-549 cell | - |
Homo sapiens | - |
5.3.99.3 | DU-145 cell | - |
Homo sapiens | - |
5.3.99.3 | additional information | MPGES-1 is not detected in LNCaP cells | Homo sapiens | - |
5.3.99.3 | PC-3 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | Prostaglandin H2 | - |
Homo sapiens | Prostaglandin E2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.3 | microsomal prostaglandin E synthase 1 | - |
Homo sapiens |
5.3.99.3 | mPGES-1 | - |
Homo sapiens |
EC Number | Organism | Comment | Expression |
---|---|---|---|
5.3.99.3 | Homo sapiens | interleukin-1beta does not change expression of MPGES-1 in the prostate cancer cell lines | additional information |