EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.5.1.29 | additional information | geranyl phosphate synthase small subunit of Antirrhinum majus forms chimeric geranyl phosphate synthases with geranylgeranyl diphosphate synthase GGPPS1 or GGPPS2 in Nicotiana tabacum. The formation of chimeric GPPS in transgenic plants also results in leaf chlorosis, increased light sensitivity, and dwarfism due to decreased levels of chlorophylls, carotenoids, and gibberellins. Transgenic plants have reduced levels of sesquiterpene emission | Antirrhinum majus |
2.5.1.29 | additional information | isoforms GGPPS2 and GGPPS1 can form functional heterodimers with heterologously expressed geranyl phosphate synthase small subunit of Antirrhinum majus. The formation of chimeric GPPS in transgenic plants also results in leaf chlorosis, increased light sensitivity, and dwarfism due to decreased levels of chlorophylls, carotenoids, and gibberellins. Transgenic plants have reduced levels of sesquiterpene emission | Nicotiana tabacum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.5.1.29 | 0.00236 | - |
geranyl diphosphate | GGPPS2 | Nicotiana tabacum | |
2.5.1.29 | 0.00363 | - |
geranyl diphosphate | GGPPS1 | Nicotiana tabacum | |
2.5.1.29 | 0.0093 | - |
isopentenyl diphosphate | heterodimer of geranyl phosphate synthase small subunit of Antirrhinum majus with Nicotiana tabacum geranylgeranyl diphosphate synthase GGPPS1 | Antirrhinum majus | |
2.5.1.29 | 0.0093 | - |
isopentenyl diphosphate | heterodimer of GGPPS1 with geranyl phosphate synthase small subunit of Antirrhinum majus | Nicotiana tabacum | |
2.5.1.29 | 0.0155 | - |
dimethylallyl diphosphate | GGPPS2 | Nicotiana tabacum | |
2.5.1.29 | 0.0195 | - |
dimethylallyl diphosphate | cosubstrate geranyl diphosphate, GGPPS2 | Nicotiana tabacum | |
2.5.1.29 | 0.0197 | - |
dimethylallyl diphosphate | cosubstrate geranyl diphosphate, GGPPS1 | Nicotiana tabacum | |
2.5.1.29 | 0.0201 | - |
dimethylallyl diphosphate | cosubstrate farnesyl diphosphate, GGPPS2 | Nicotiana tabacum | |
2.5.1.29 | 0.0206 | - |
isopentenyl diphosphate | GGPPS1 | Nicotiana tabacum | |
2.5.1.29 | 0.0206 | - |
isopentenyl diphosphate | GGPPS2 | Nicotiana tabacum | |
2.5.1.29 | 0.0206 | - |
isopentenyl diphosphate | heterodimer of geranyl phosphate synthase small subunit of Antirrhinum majus with Nicotiana tabacum geranylgeranyl diphosphate synthase GGPPS1 | Antirrhinum majus | |
2.5.1.29 | 0.0206 | - |
isopentenyl diphosphate | heterodimer of GGPPS2 with geranyl phosphate synthase small subunit of Antirrhinum majus | Nicotiana tabacum | |
2.5.1.29 | 0.0228 | - |
dimethylallyl diphosphate | GGPPS1 | Nicotiana tabacum | |
2.5.1.29 | 0.0277 | - |
dimethylallyl diphosphate | cosubstrate farnesyl diphosphate, GGPPS1 | Nicotiana tabacum | |
2.5.1.29 | 0.0288 | - |
farnesyl diphosphate | GGPPS1 | Nicotiana tabacum | |
2.5.1.29 | 0.029 | - |
dimethylallyl diphosphate | heterodimer of geranyl phosphate synthase small subunit of Antirrhinum majus with Nicotiana tabacum geranylgeranyl diphosphate synthase GGPPS2 | Antirrhinum majus | |
2.5.1.29 | 0.029 | - |
dimethylallyl diphosphate | heterodimer of GGPPS2 with geranyl phosphate synthase small subunit of Antirrhinum majus | Nicotiana tabacum | |
2.5.1.29 | 0.0532 | - |
farnesyl diphosphate | GGPPS2 | Nicotiana tabacum | |
2.5.1.29 | 0.0589 | - |
dimethylallyl diphosphate | heterodimer of geranyl phosphate synthase small subunit of Antirrhinum majus with Nicotiana tabacum geranylgeranyl diphosphate synthase GGPPS2 | Antirrhinum majus | |
2.5.1.29 | 0.0589 | - |
dimethylallyl diphosphate | heterodimer of GGPPS1 with geranyl phosphate synthase small subunit of Antirrhinum majus | Nicotiana tabacum |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.29 | plastid | - |
Nicotiana tabacum | 9536 | - |
2.5.1.29 | plastid | - |
Antirrhinum majus | 9536 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.29 | MgCl2 | Km value 0.51 mM for isoform GGPPS1, 0.19 mM for isoform GGPPS2 | Nicotiana tabacum |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.29 | Antirrhinum majus | - |
- |
- |
2.5.1.29 | Nicotiana tabacum | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.29 | (E,E)-farnesyl diphosphate + isopentenyl diphosphate | isoforms TC5826 and TC11329, i.e. GGPPS2 and GGPPS1, respectively | Nicotiana tabacum | diphosphate + geranylgeranyl diphosphate | - |
? | |
2.5.1.29 | dimethylallyl diphosphate + 3 isopentenyl diphosphate | - |
Antirrhinum majus | geranylgeranyl diphosphate + 3 diphosphate | - |
? | |
2.5.1.29 | dimethylallyl diphosphate + 3 isopentenyl diphosphate | isoforms TC5826 and TC11329, i.e. GGPPS2 and GGPPS1, respectively | Nicotiana tabacum | geranylgeranyl diphosphate + diphosphate | - |
? | |
2.5.1.29 | geranyl diphosphate + 2 isopentenyl diphosphate | isoforms TC5826 and TC11329, i.e. GGPPS2 and GGPPS1, respectively | Nicotiana tabacum | geranylgeranyl diphosphate + diphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.5.1.29 | More | geranyl phosphate synthase small subunit of Antirrhinum majus forms chimeric geranyl phosphate synthases with geranylgeranyl diphosphate synthase GGPPS1 or GGPPS2 in Nicotiana tabacum | Antirrhinum majus |
2.5.1.29 | More | isoforms GGPPS2 and GGPPS! can form functional heterodimers with heterologously expressed geranyl phosphate synthase small subunit of Antirrhinum majus | Nicotiana tabacum |