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Literature summary extracted from

  • Lee, U.; Wie, C.; Fernandez, B.O.; Feelisch, M.; Vierling, E.
    Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis (2008), Plant Cell, 20, 786-802.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.284 E283K activity compared with the wild type is 33.8% in hot5-1 plants. No significant change in GSNOR activity under heat stress conditions in the wild-type or mutant. Dark-grown seedlings of hot5-1 have a heat-stress phenotype in the dark, despite having apparently reasonable GSNOR activity at this stage Arabidopsis thaliana
1.1.1.284 G288R activity compared with the wild type is 58.8% in hot5-3 plants. No significant change in GSNOR activity under heat stress conditions in the wild-type or mutant. Dark-grown seedlings of hot5-3 have a heat-stress phenotype in the dark, despite having apparently reasonable GSNOR activity at this stage Arabidopsis thaliana
1.1.1.284 additional information thermotolerance-defective mutant hot5, which encodes GSNOR. Hot5 missense alleles cannot acclimate to heat as dark-grown seedlings but grow normally and can heat-acclimate in the light. The null alleles cannot heat-acclimate as light-grown plants and have other phenotypes, including failure to grow on nutrient plates, increased reproductive shoots, and reduced fertility. The fertility defect of hot5 is due to both reduced stamen elongation and male and female fertilization defects. The hot5 null alleles show increased nitrate and nitroso species levels, and the heat sensitivity of both missense and null alleles is associated with increased NO species. Heat sensitivity is enhanced in wild-type and mutant plants by NO donors, and the heat sensitivity of hot5 mutants can be rescued by an NO scavenger. An NO-overproducing mutant is also defective in thermotolerance Arabidopsis thaliana

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.284 40000
-
-
 Arabidopsis thaliana

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.284 Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.284 leaf
-
 Arabidopsis thaliana
-
1.1.1.284 seed dried seeds Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.284 S-nitrosoglutathione + NADH + H+
-
 Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.284 GSNOR
-
 Arabidopsis thaliana
1.1.1.284 HOT5
-
 Arabidopsis thaliana
1.1.1.284 S-nitrosoglutathione reductase
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.284 NADH
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
1.1.1.284 Arabidopsis thaliana GSNOR is not heat induced additional information

General Information

EC Number General Information Comment Organism
1.1.1.284 physiological function importance of GSNOR-regulated NO homeostasis to abiotic stress and plant development. GSNOR affects intracellular NO/nitrosation levels Arabidopsis thaliana