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Literature summary extracted from

  • Cao, H.; Li, Y.; Lau, K.; Muthana, S.; Yu, H.; Cheng, J.; Chokhawala, H.A.; Sugiarto, G.; Zhang, L.; Chen, X.
    Sialidase substrate specificity studies using chemoenzymatically synthesized sialosides containing C5-modified sialic acids (2009), Org. Biomol. Chem., 7, 5137-5145.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.18 Clostridium perfringens
-
-
-
3.2.1.18 Pasteurella multocida
-
-
-
3.2.1.18 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
3.2.1.18 Streptococcus pneumoniae
-
-
-
3.2.1.18 Vibrio cholerae serotype O1
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-5-fluoro-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O about 30% cleavage Clostridium perfringens ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O about 5% cleavage Clostridium perfringens ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(3-deoxy-5-O-methyl-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-(5-azido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid)-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O less than 10% cleavage Clostridium perfringens ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-azidoacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O less than 5% cleavage Clostridium perfringens ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O about 50% cleavage Clostridium perfringens ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-fluoroacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O about 35% cleavage Clostridium perfringens ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Streptococcus pneumoniae ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Vibrio cholerae serotype O1 ?
-
 ?
3.2.1.18 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside + H2O
-
 Pasteurella multocida ?
-
 ?
3.2.1.18 additional information no cleavage of 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-3)-O-beta-D-galactopyranoside and 4-nitrophenyl O-[5-(2-methoxyacetamido)-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosylonic acid]-(2-6)-O-beta-D-galactopyranoside Clostridium perfringens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.18 sialidase
-
 Salmonella enterica subsp. enterica serovar Typhimurium
3.2.1.18 sialidase
-
 Streptococcus pneumoniae
3.2.1.18 sialidase
-
 Clostridium perfringens
3.2.1.18 sialidase
-
 Vibrio cholerae serotype O1
3.2.1.18 sialidase
-
 Pasteurella multocida