EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.5 | (3S)-3-amino-1-bromo-4-methylhexan-2-one | labeling reagent | Escherichia coli | |
6.1.1.5 | (3S)-3-amino-1-bromo-4-methylpentan-2-one | labeling reagent | Escherichia coli | |
6.1.1.5 | (3S)-3-amino-1-bromo-4-phenylbutan-2-one | labeling reagent | Escherichia coli | |
6.1.1.5 | (3S)-3-amino-1-bromoheptan-2-one | labeling reagent | Escherichia coli | |
6.1.1.5 | 2',3'-dialdehyde of tRNAile | used to label the binding site for the 3'end of tRNA on the synthetase, incubation of the reagent with IleRS results in a rapid loss of tRNAIle aminoacylation and isoleucine-dependent isotopic ATP-PPi exchange activities | Escherichia coli | |
6.1.1.5 | diethyl dicarbonate | - |
Escherichia coli | |
6.1.1.5 | pyridoxal 5'-diphospho-5'-adenosine | affinity labeling reagent for the ATP-binding site, incubation of the reagent with IleRS results in a rapid loss of tRNAIle aminoacylation and isoleucine-dependent isotopic ATP-PPi exchange activities | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.5 | ATP + L-isoleucine + tRNAIle | Escherichia coli | - |
AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? | |
6.1.1.5 | ATP + L-isoleucine + tRNAIle | Escherichia coli EM20031 | - |
AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.1.1.5 | Escherichia coli | - |
- |
- |
6.1.1.5 | Escherichia coli EM20031 | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.1.1.5 | - |
Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.5 | ATP + L-isoleucine + tRNAIle | - |
Escherichia coli | AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? | |
6.1.1.5 | ATP + L-isoleucine + tRNAIle | - |
Escherichia coli EM20031 | AMP + diphosphate + L-isoleucyl-tRNAIle | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.1.1.5 | IleRS | - |
Escherichia coli |
6.1.1.5 | Isoleucyl-tRNA synthetase | - |
Escherichia coli |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.5 | ATP | - |
Escherichia coli |