Literature summary extracted from

Funamizu, N.; Okamoto, A.; Kamata, Y.; Misawa, T.; Uwagawa, T.; Gocho, T.; Yanaga, K.; Manome, Y.
Is the resistance of gemcitabine for pancreatic cancer settled only by overexpression of deoxycytidine kinase? (2010), Oncol. Rep., 23, 471-475.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.74	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.74	BxPC-3 cell	-	Homo sapiens	-
2.7.1.74	MiaPaCa-2 cell	-	Homo sapiens	-
2.7.1.74	PANC-1 cell	-	Homo sapiens	-
2.7.1.74	pancreatic cancer cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.74	ATP + 2'-deoxycytidine	-	Homo sapiens	ADP + 2'-deoxycytidine 5'-phosphate	-	?
2.7.1.74	ATP + gemcitabine	i.e. difluorodeoxycytidine	Homo sapiens	ADP + gemcitabine 5'-phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.1.74	dCK	-	Homo sapiens

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.7.1.74	ATP	-	Homo sapiens

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Release 2023.1 (January 2023)