Literature summary extracted from

Fyrberg, A.; Albertioni, F.; Lotfi, K.
RNAi depletion of deoxycytidine and deoxyguanosine kinase in human leukemic CEM cells (2008), Nucleosides Nucleotides Nucleic Acids, 27, 712-719.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.113	2-fluoro-9-beta-D-arabinofuranosyladenine	-	Homo sapiens
2.7.1.113	9-beta-D-arabinofuranosylguanine	-	Homo sapiens
2.7.1.113	cladribine	-	Homo sapiens
2.7.1.113	clofarabine	-	Homo sapiens
2.7.1.113	cytarabine	-	Homo sapiens
2.7.1.113	gemcitabine	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.113	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.113	CEM cell	-	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.1.113	DGK	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
2.7.1.113	malfunction	dGK depletion in cells results in lower sensitivity to 2-fluoro-9-beta-D-arabinofuranosyladenine, gemcitabine, clofarabine, and 9-beta-D-arabinofuranosylguanine, but slightly higher sensitivity to cladribine and cytarabine	Homo sapiens

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Release 2023.1 (January 2023)