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Literature summary extracted from

  • Okamoto, S.; Tamaru, A.; Nakajima, C.; Nishimura, K.; Tanaka, Y.; Tokuyama, S.; Suzuki, Y.; Ochi, K.
    Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria (2007), Mol. Microbiol., 63, 1096-1106.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.170
-
 Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
2.1.1.170 additional information mutations within the gene gidB confer low-level streptomycin resistance. gidB mutations emerge spontaneously at a high frequency of 0.000001 and, once emerged, result in vigorous emergence of high-level streptomycin-resistant mutants at a frequency more than 2000 times greater than that seen in wild-type strains Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.170 Escherichia coli
-
-
-
2.1.1.170 Escherichia coli BW25113
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.170
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.170 S-adenosyl-L-methionine + guanine527 in 16S rRNA GidB is a m7G methyltransferase specific for 16S rRNA, identification of methylated nucleotide Escherichia coli S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA
-
 ?
2.1.1.170 S-adenosyl-L-methionine + guanine527 in 16S rRNA GidB is a m7G methyltransferase specific for 16S rRNA, identification of methylated nucleotide Escherichia coli BW25113 S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.170 gidB
-
 Escherichia coli

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.1.1.170 37
-
 assay at Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.1.1.170 7.5
-
 assay at Escherichia coli

General Information

EC Number General Information Comment Organism
2.1.1.170 malfunction mutations within the gene gidB confer low-level streptomycin resistance. gidB Mmutations emerge spontaneously at a high frequency of 0.000001 and, once emerged, result in vigorous emergence of high-level streptomycin-resistant mutants at a frequency more than 2000 times greater than that seen in wild-type strains Escherichia coli