BRENDA - Enzyme Database

Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

Ren, F.; Wu, H.; Lei, Y.; Zhang, H.; Liu, R.; Zhao, Y.; Chen, X.; Zeng, D.; Tong, A.; Chen, L.; Wei, Y.; Huang, C.; Mol. Cancer 9, 81 (2010)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
5.4.2.11
medicine
PGAM1 plays an important role in hepatocarcinogenesis, is a potential diagnostic biomarker as well as an attractive therapeutic target for hepatocellular carcinoma
Homo sapiens
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
5.4.2.11
28900
-
calculated from amino acid sequence
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.4.2.11
2-phospho-D-glycerate
Homo sapiens
-
3-phospho-D-glycerate
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.4.2.11
Homo sapiens
P18669
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.2.11
Hep-G2 cell
-
Homo sapiens
-
5.4.2.11
hepatocellular carcinoma cell
-
Homo sapiens
-
5.4.2.11
liver
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.2.11
2-phospho-D-glycerate
-
705672
Homo sapiens
3-phospho-D-glycerate
-
-
-
?
pI Value
EC Number
Organism
Commentary
pI Value Maximum
pI Value
5.4.2.11
Homo sapiens
calculated from amino acid sequence
-
6.7
Application (protein specific)
EC Number
Application
Commentary
Organism
5.4.2.11
medicine
PGAM1 plays an important role in hepatocarcinogenesis, is a potential diagnostic biomarker as well as an attractive therapeutic target for hepatocellular carcinoma
Homo sapiens
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
5.4.2.11
28900
-
calculated from amino acid sequence
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.4.2.11
2-phospho-D-glycerate
Homo sapiens
-
3-phospho-D-glycerate
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.4.2.11
Hep-G2 cell
-
Homo sapiens
-
5.4.2.11
hepatocellular carcinoma cell
-
Homo sapiens
-
5.4.2.11
liver
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.4.2.11
2-phospho-D-glycerate
-
705672
Homo sapiens
3-phospho-D-glycerate
-
-
-
?
pI Value (protein specific)
EC Number
Organism
Commentary
pI Value Maximum
pI Value
5.4.2.11
Homo sapiens
calculated from amino acid sequence
-
6.7