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Literature summary extracted from

  • Ren, F.; Wu, H.; Lei, Y.; Zhang, H.; Liu, R.; Zhao, Y.; Chen, X.; Zeng, D.; Tong, A.; Chen, L.; Wei, Y.; Huang, C.
    Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma (2010), Mol. Cancer, 9, 81.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
5.4.2.11 medicine PGAM1 plays an important role in hepatocarcinogenesis, is a potential diagnostic biomarker as well as an attractive therapeutic target for hepatocellular carcinoma Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.4.2.11 28900
-
 calculated from amino acid sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.2.11 2-phospho-D-glycerate Homo sapiens
-
 3-phospho-D-glycerate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.11 Homo sapiens P18669
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.2.11 Hep-G2 cell
-
 Homo sapiens
-
5.4.2.11 hepatocellular carcinoma cell
-
 Homo sapiens
-
5.4.2.11 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.11 2-phospho-D-glycerate
-
 Homo sapiens 3-phospho-D-glycerate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.2.11 PGAM1
-
 Homo sapiens
5.4.2.11 phosphoglycerate mutase 1
-
 Homo sapiens

pI Value

EC Number Organism Comment pI Value Maximum pI Value
5.4.2.11 Homo sapiens calculated from amino acid sequence
-
 6.7