EC Number | Application | Comment | Organism |
---|---|---|---|
2.7.11.10 | medicine | inhibition of IkappaB kinase beta induces growth suppression and death in cells expressing wild-type, Imatinib-resistant, or the T315I Imatinib/Dasatinib-resistant forms of BCR-ABL | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.10 | ATP + [IkappaB protein] | Mus musculus | - |
ADP + [IkappaB phosphoprotein] | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.10 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.10 | 32D cell | - |
Mus musculus | - |
2.7.11.10 | BA/F3 cell | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.10 | ATP + [IkappaB protein] | - |
Mus musculus | ADP + [IkappaB phosphoprotein] | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.10 | IkappaB kinase beta | - |
Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.10 | ATP | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.11.10 | physiological function | IkappaB kinase beta is a key upstream regulator of the NF-kappaB pathway | Mus musculus |