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Literature summary extracted from

  • Lo, C.C.; Bonner, C.A.; Xie, G.; DSouza, M.; Jensen, R.A.
    Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways (2009), Microbiol. Mol. Biol. Rev., 73, 594-651.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.2.4 ATP + L-aspartate Escherichia coli
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Saccharomyces cerevisiae
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Pyrococcus furiosus
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Myxococcus xanthus
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Bdellovibrio bacteriovorus
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Methanopyrus kandleri
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Thermotoga maritima
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Chlamydia sp.
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Aquifex aeolicus
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Leptospira interrogans
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Maricaulis maris
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Corynebacterium glutamicum
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Thermotoga petrophila
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Francisella tularensis subsp. novicida
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Leptospira borgpetersenii
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Francisella tularensis subsp. novicida U112
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Maricaulis maris MCS10
-
 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate Bdellovibrio bacteriovorus HD100
-
 ADP + 4-phospho-L-aspartate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.4 Aquifex aeolicus
-
-
-
2.7.2.4 Bdellovibrio bacteriovorus
-
-
-
2.7.2.4 Bdellovibrio bacteriovorus HD100
-
-
-
2.7.2.4 Chlamydia sp.
-
-
-
2.7.2.4 Corynebacterium glutamicum P26512
-
-
2.7.2.4 Escherichia coli
-
-
-
2.7.2.4 Francisella tularensis subsp. novicida
-
-
-
2.7.2.4 Francisella tularensis subsp. novicida U112
-
-
-
2.7.2.4 Leptospira borgpetersenii
-
-
-
2.7.2.4 Leptospira interrogans
-
-
-
2.7.2.4 Maricaulis maris
-
-
-
2.7.2.4 Maricaulis maris MCS10
-
-
-
2.7.2.4 Methanopyrus kandleri
-
-
-
2.7.2.4 Myxococcus xanthus
-
-
-
2.7.2.4 Pyrococcus furiosus
-
-
-
2.7.2.4 Saccharomyces cerevisiae
-
-
-
2.7.2.4 Thermotoga maritima
-
-
-
2.7.2.4 Thermotoga petrophila
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.4 ATP + L-aspartate
-
 Escherichia coli ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Saccharomyces cerevisiae ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Pyrococcus furiosus ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Myxococcus xanthus ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Bdellovibrio bacteriovorus ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Methanopyrus kandleri ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Thermotoga maritima ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Chlamydia sp. ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Aquifex aeolicus ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Leptospira interrogans ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Maricaulis maris ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Corynebacterium glutamicum ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Thermotoga petrophila ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Francisella tularensis subsp. novicida ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Leptospira borgpetersenii ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Francisella tularensis subsp. novicida U112 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Maricaulis maris MCS10 ADP + 4-phospho-L-aspartate
-
 ?
2.7.2.4 ATP + L-aspartate
-
 Bdellovibrio bacteriovorus HD100 ADP + 4-phospho-L-aspartate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.2.4 Ask
-
 Escherichia coli
2.7.2.4 Ask
-
 Saccharomyces cerevisiae
2.7.2.4 Ask
-
 Pyrococcus furiosus
2.7.2.4 Ask
-
 Myxococcus xanthus
2.7.2.4 Ask
-
 Bdellovibrio bacteriovorus
2.7.2.4 Ask
-
 Methanopyrus kandleri
2.7.2.4 Ask
-
 Thermotoga maritima
2.7.2.4 Ask
-
 Chlamydia sp.
2.7.2.4 Ask
-
 Aquifex aeolicus
2.7.2.4 Ask
-
 Leptospira interrogans
2.7.2.4 Ask
-
 Maricaulis maris
2.7.2.4 Ask
-
 Corynebacterium glutamicum
2.7.2.4 Ask
-
 Thermotoga petrophila
2.7.2.4 Ask
-
 Francisella tularensis subsp. novicida
2.7.2.4 Ask
-
 Leptospira borgpetersenii
2.7.2.4 aspartokinase
-
 Escherichia coli
2.7.2.4 aspartokinase
-
 Saccharomyces cerevisiae
2.7.2.4 aspartokinase
-
 Pyrococcus furiosus
2.7.2.4 aspartokinase
-
 Myxococcus xanthus
2.7.2.4 aspartokinase
-
 Bdellovibrio bacteriovorus
2.7.2.4 aspartokinase
-
 Methanopyrus kandleri
2.7.2.4 aspartokinase
-
 Thermotoga maritima
2.7.2.4 aspartokinase
-
 Chlamydia sp.
2.7.2.4 aspartokinase
-
 Aquifex aeolicus
2.7.2.4 aspartokinase
-
 Leptospira interrogans
2.7.2.4 aspartokinase
-
 Maricaulis maris
2.7.2.4 aspartokinase
-
 Corynebacterium glutamicum
2.7.2.4 aspartokinase
-
 Thermotoga petrophila
2.7.2.4 aspartokinase
-
 Francisella tularensis subsp. novicida
2.7.2.4 aspartokinase
-
 Leptospira borgpetersenii