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Literature summary extracted from

  • Pacheco, G.S.; Panatto, J.P.; Fagundes, D.A.; Scaini, G.; Bassani, C.; Jeremias, I.C.; Rezin, G.T.; Constantino, L.; Dal-Pizzol, F.; Streck, E.L.
    Brain creatine kinase activity is inhibited after hepatic failure induced by carbon tetrachloride or acetaminophen (2009), Metab. Brain Dis., 24, 383-394.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.3.2 acetaminophen inhibits creatine kinase in cerebellum and hippocampus, the administration of N-acetylcysteine plus deferoxamine reverses the inhibition of creatine kinase activity Rattus norvegicus
2.7.3.2 carbon tetrachloride inhibits creatine kinase activity in cerebellum, the administration of N-acetylcysteine plus deferoxamine reverses the inhibition of creatine kinase activity Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.3.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.3.2 cerebellum
-
 Rattus norvegicus
-
2.7.3.2 cerebral cortex
-
 Rattus norvegicus
-
2.7.3.2 hippocampus
-
 Rattus norvegicus
-
2.7.3.2 prefrontal cortex
-
 Rattus norvegicus
-
2.7.3.2 striatum
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.3.2 ATP + creatine
-
 Rattus norvegicus ADP + creatine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.3.2 brain creatine kinase
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.3.2 ATP
-
 Rattus norvegicus