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Literature summary extracted from

  • Tonin, A.M.; Ferreira, G.C.; Schuck, P.F.; Viegas, C.M.; Zanatta, A.; Leipnitz, G.; Seminotti, B.; Duvall Wannmacher, C.M.; Wajner, M.
    Inhibition of creatine kinase activity by lysine in rat cerebral cortex (2009), Metab. Brain Dis., 24, 349-360.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.3.2 L-lysine total and cytosolic creatine kinase activities are significantly inhibited by L-lysine, in contrast to the mitochondrial isoform which is not affected, the inhibitory effect of L-lysine on total creatine kinase activity is totally prevented by reduced glutathione Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.3.2 cytosol
-
 Rattus norvegicus 5829
-
2.7.3.2 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.3.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.3.2 cerebral cortex
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.3.2 ATP + creatine
-
 Rattus norvegicus ADP + creatine phosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.3.2 ATP
-
 Rattus norvegicus