BRENDA - Enzyme Database

Multifunctional roles of enolase in Alzheimers disease brain: beyond altered glucose metabolism

Butterfield, D.A.; Lange, M.L.; J. Neurochem. 111, 915-933 (2009)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.2.1.11
cytosol
-
Homo sapiens
5829
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.2.1.11
48000
-
alpha-enolase
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
brain
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
705257
Homo sapiens
phosphoenolpyruvate + H2O
-
-
-
r
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.2.1.11
cytosol
-
Homo sapiens
5829
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.2.1.11
48000
-
alpha-enolase
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
brain
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
705257
Homo sapiens
phosphoenolpyruvate + H2O
-
-
-
r
Expression
EC Number
Organism
Commentary
Expression
4.2.1.11
Homo sapiens
alpha-enolase is consistently up-regulated from mild cognitive impairment to Alzheimer's disease
up
General Information
EC Number
General Information
Commentary
Organism
4.2.1.11
metabolism
alpha-enolase is involved in glucose metabolism in Alzheimer's disease brain
Homo sapiens
4.2.1.11
physiological function
glycolytic/gluconeogenesis enzyme, eye lens tau-crystallin protein, plasminogen binding protein, c-Myc binding protein and transcription factor in tumor formationk
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
4.2.1.11
metabolism
alpha-enolase is involved in glucose metabolism in Alzheimer's disease brain
Homo sapiens
4.2.1.11
physiological function
glycolytic/gluconeogenesis enzyme, eye lens tau-crystallin protein, plasminogen binding protein, c-Myc binding protein and transcription factor in tumor formationk
Homo sapiens
Expression (protein specific)
EC Number
Organism
Commentary
Expression
4.2.1.11
Homo sapiens
alpha-enolase is consistently up-regulated from mild cognitive impairment to Alzheimer's disease
up