Literature summary extracted from

Lebars, I.; Husson, C.; Yoshizawa, S.; Douthwaite, S.; Fourmy, D.
Recognition elements in rRNA for the tylosin resistance methyltransferase RlmA(II) (2007), J. Mol. Biol., 372, 525-534.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.1.1.188	-	Streptococcus pneumoniae

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.188	Streptococcus pneumoniae	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.1.1.188	-	Streptococcus pneumoniae

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.188	S-adenosyl-L-methionine + guanine748 in 23S rRNA	progressive truncation of the rRNA substrate indicates that multiple contacts occur between RlmAII and nucleotides in stemloops 33, 34 and 35. RlmAII appears to recognize its rRNA target through specific surface shape complementarity at the junction formed by these three helices	Streptococcus pneumoniae	S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.188	RlmA(II)	-	Streptococcus pneumoniae
2.1.1.188	tylosin resistance methyltransferase RlmA(II)	-	Streptococcus pneumoniae

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Release 2023.1 (January 2023)