EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.2 | Mg2+ | - |
Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
5.3.99.2 | into the vector pT7-7 for expression in Escherichia coli BL21DE3 cells | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
5.3.99.2 | Y8F | active site mutant | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.2 | Mg2+ | - |
Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
5.3.99.2 | 23000 | - |
monomer | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.2 | Prostaglandin H2 | Homo sapiens | - |
Prostaglandin D2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.2 | Homo sapiens | O60760 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
5.3.99.2 | by ammonium sulfate precipitation, and on a GSH Sepharose 4B and a Superdex 75 pg column | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.2 | Prostaglandin H2 | - |
Homo sapiens | Prostaglandin D2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
5.3.99.2 | homodimer | 2 * 23000 Da | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.2 | H-PGDS | - |
Homo sapiens |
5.3.99.2 | hematopoietic prostaglandin D2 synthase | - |
Homo sapiens |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
5.3.99.2 | 25 | - |
kinetic assay | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
5.3.99.2 | 8 | - |
kinetic assay | Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.2 | glutathione | - |
Homo sapiens |