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Literature summary extracted from

  • Dixon, D.P.; Hawkins, T.; Hussey, P.J.; Edwards, R.
    Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily (2009), J. Exp. Bot., 60, 1207-1218.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.18 functional expression of 41 GST genes in Escherichia coli strain Tuner(DE3), phylogenetic tree, expression of theta class GSTs as GFP-fusion proteins in Nicotiana benthamiana peroxisomes via the Agrobacterium tumefaciens transfection system. Through alternative splicing, two of these GSTTs form fusions with Myb transcription factor-like domains. Examination of one of these variants showed discrete localization within the nucleus, possibly serving a role in reducing nucleic acid hydroperoxides or in signalling Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.18 additional information subcellular localization of members of the Arabidopsis thaliana GST superfamily, differential targeting, overview Arabidopsis thaliana
-
-
2.5.1.18 nucleus through alternative splicing, two of these GSTTs form fusions with Myb transcription factor-like domains, discrete localization within the nucleus Arabidopsis thaliana 5634
-
2.5.1.18 peroxisome GFP-tagged recombinant theta class GSTs Arabidopsis thaliana 5777
-

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.18 Arabidopsis thaliana Q9FUS8 54 GST genes of the Arabidopsis thaliana GST superfamily
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.18 benzyl isothiocyanate + glutathione
-
 Arabidopsis thaliana ?
-
 ?
2.5.1.18 cumene hydroperoxide + glutathione
-
 Arabidopsis thaliana ?
-
 ?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Arabidopsis thaliana S-(2,4-dinitrophenyl)glutathione + HCl
-
 ?
2.5.1.18 additional information three recombinant theta class GSTs, GSTTs, show conserved activities as hydroperoxide-reducing glutathione peroxidases Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.18 GST
-
 Arabidopsis thaliana
2.5.1.18 GSTT
-
 Arabidopsis thaliana
2.5.1.18 theta class GST
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
2.5.1.18 physiological function through alternative splicing, two of these GSTTs form fusions with Myb transcription factor-like domains, discrete localization within the nucleus, possibly serving role in reducing nucleic acid hydroperoxides or in signalling Arabidopsis thaliana