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Literature summary extracted from

  • Clerc, S.; Hirsch, C.; Oggier, D.M.; Deprez, P.; Jakob, C.; Sommer, T.; Aebi, M.
    Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum (2009), J. Cell Biol., 184, 159-172.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.210 endoplasmic reticulum
-
 Saccharomyces cerevisiae 5783
-

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.210 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.210 ultracentrifugation and IgG bead column chromatography Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.210 Man8GlcNAc2 + H2O
-
 Saccharomyces cerevisiae Man7GlcNAc2 + D-mannose
-
 ?
3.2.1.210 Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)[Manalpha(1-2)Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc + H2O
-
 Saccharomyces cerevisiae Manalpha(1-2)Manalpha(1-3)[Manalpha(1-2)Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc + D-mannose
-
 ?
3.2.1.210 additional information the Htm1p exomannosidase activity requires processing of the N-glycan by glucosidase I, glucosidase II, and mannosidase I Saccharomyces cerevisiae ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.210 alpha1,2-specific exomannosidase
-
 Saccharomyces cerevisiae
3.2.1.210 Htm1 protein
-
 Saccharomyces cerevisiae
3.2.1.210 Htm1p
-
 Saccharomyces cerevisiae

General Information

EC Number General Information Comment Organism
3.2.1.210 physiological function Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. Htm1p physically interacts with Pdi1p via its C-terminal domain Saccharomyces cerevisiae