BRENDA - Enzyme Database

Pyruvate:quinone oxidoreductase in Corynebacterium glutamicum: molecular analysis of the pqo gene, significance of the enzyme, and phylogenetic aspects

Schreiner, M.E.; Riedel, C.; Holatko, J.; Patek, M.; Eikmanns, B.J.; J. Bacteriol. 188, 1341-1350 (2006)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.2.5.1
pyruvate + a quinone
Corynebacterium glutamicum
-
acetate + CO2 + a quinol
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.2.5.1
Corynebacterium glutamicum
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.2.5.1
pyruvate + a quinone
-
704267
Corynebacterium glutamicum
acetate + CO2 + a quinol
-
-
-
?
1.2.5.1
pyruvate + oxidized 2,6-dichloroindophenol
activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol, pH 6.0, 40°C
704267
Corynebacterium glutamicum
acetate + CO2 + reduced 2,6-dichloroindophenol
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.2.5.1
pyruvate + a quinone
Corynebacterium glutamicum
-
acetate + CO2 + a quinol
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.2.5.1
pyruvate + a quinone
-
704267
Corynebacterium glutamicum
acetate + CO2 + a quinol
-
-
-
?
1.2.5.1
pyruvate + oxidized 2,6-dichloroindophenol
activity assayed photometrically by monitoring the reduction of 2,6-dichloroindophenol, pH 6.0, 40°C
704267
Corynebacterium glutamicum
acetate + CO2 + reduced 2,6-dichloroindophenol
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
1.2.5.1
physiological function
inactivation of the chromosomal pqo gene leads to the absence of pyruvate:quinone oxidoreductase activity. Growth and amino acid production are not affected under either condition tested. Introduction of plasmid-bound pqo into a pyruvate dehydrogenase complex-negative strain partially relieves the growth phenotype of this mutant, indicating that high pyruvate:quinone oxidoreductase activity can compensate for the function of the pyruvate dehydrogenase complex
Corynebacterium glutamicum
General Information (protein specific)
EC Number
General Information
Commentary
Organism
1.2.5.1
physiological function
inactivation of the chromosomal pqo gene leads to the absence of pyruvate:quinone oxidoreductase activity. Growth and amino acid production are not affected under either condition tested. Introduction of plasmid-bound pqo into a pyruvate dehydrogenase complex-negative strain partially relieves the growth phenotype of this mutant, indicating that high pyruvate:quinone oxidoreductase activity can compensate for the function of the pyruvate dehydrogenase complex
Corynebacterium glutamicum