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Literature summary extracted from

  • Young, I.G.; Leppik, R.A.; Hamilton, J.A.; Gibson, F.
    Biochemical and genetic studies on ubiquinone biosynthesis in Escherichia coli K-12 4-hydroxybenzoate octaprenyltransferase (1972), J. Bacteriol., 110, 18-25.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.39 Ca2+ inhibitory effect Escherichia coli
2.5.1.39 Cd2+ inhibitory effect Escherichia coli
2.5.1.39 Cu2+ inhibitory effect Escherichia coli
2.5.1.39 Fe2+ inhibitory effect Escherichia coli
2.5.1.39 Zn2+ inhibitory effect Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.39 membrane membrane-bound protein Escherichia coli 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.39 Co2+ partly effective for activity Escherichia coli
2.5.1.39 Mg2+ required for optimal activity Escherichia coli
2.5.1.39 Mn2+ less effective for activity Escherichia coli
2.5.1.39 Ni2+ partly effective for activity Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.39 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.39 octaprenyl diphosphate + 4-hydroxybenzoate
-
 Escherichia coli 4-hydroxy-3-octaprenylbenzoate + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.39 4-hydroxybenzoate octaprenyltransferase
-
 Escherichia coli
2.5.1.39 ubiA
-
 Escherichia coli

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.5.1.39 37
-
 assay at Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.39 7
-
 assay at Escherichia coli

General Information

EC Number General Information Comment Organism
2.5.1.39 malfunction ubiA knockout mutants are deficient in 4-hydroxybenzoate octaprenyltransferase activity Escherichia coli