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Literature summary extracted from
- Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2,3-dioxygenase involved in degradation of polychlorinated biphenyls (2010), Int. J. Biol. Macromol., 46, 47-53.
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.12.18 | Fe2+ | coordination geometry of Fe-ion along with the oxygen and different polychlorinated biphenyl congeners | Comamonas testosteroni |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.12.18 | Comamonas testosteroni | Q46372 | alpha-subunit of biphenyl dioxygenase; B-356 | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.12.18 | 3,3'-dichlorobiphenyl + NADH + H+ + O2 | - |
Comamonas testosteroni | 5,6-dihydroxy-1-phenylcyclohexa-1,3-diene + 4,5-dihydroxy-1-phenylcyclohexa-1,2-diene + NAD+ + HCl | - |
? | |
| 1.14.12.18 | 4,4'-dichlorobiphenyl + NADH + H+ + O2 | - |
Comamonas testosteroni | 2,3-dihydroxy-4,4'-dichlorobiphenyl + NAD+ | - |
? | |
| 1.14.12.18 | biphenyl + NADH + H+ + O2 | - |
Comamonas testosteroni | 2,3-dihydro-dihydroxybiphenyl + NAD+ | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.14.12.18 | ? | construction of a three-dimensional model of alpha-subunit of biphenyl dioxygenase (BphA). BphA active site is composed of two domains, the catalytic domain (residues 1-58 and 176-457) and the Rieske domain (residues 59166). The active site pocket, which is lined mostly by hydrophobic residues (Phe227, Trp390, Phe 376, Asp386, Phe382 and Ala234) is located between the core beta-sheet and alpha-helices in the catalytic domain of the alpha-subunit | Comamonas testosteroni |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.12.18 | biphenyl dioxygenase | - |
Comamonas testosteroni |
| 1.14.12.18 | biphenyl-2,3-dioxygenase | - |
Comamonas testosteroni |
| 1.14.12.18 | BPDO | - |
Comamonas testosteroni |
| 1.14.12.18 | BphA | - |
Comamonas testosteroni |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.12.18 | NADH | - |
Comamonas testosteroni | |
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