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Literature summary extracted from

  • Adamczyk-Poplawska, M.; Lower, M.; Piekarowicz, A.
    Characterization of the NgoAXP: phase-variable type III restriction-modification system in Neisseria gonorrhoeae (2009), FEMS Microbiol. Lett., 300, 25-35.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.72 expressed in Escherichia coli GM2163 cells Neisseria gonorrhoeae
3.1.21.5 expression in Escherichia coli Neisseria gonorrhoeae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.1.72 77500
-
 calculated from amino acid sequence Neisseria gonorrhoeae
3.1.21.5 77500
-
 calculated Neisseria gonorrhoeae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.72 S-adenosyl-L-methionine + DNA adenine Neisseria gonorrhoeae the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?
2.1.1.72 S-adenosyl-L-methionine + DNA adenine Neisseria gonorrhoeae FA 1090 the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.72 Neisseria gonorrhoeae
-
-
-
2.1.1.72 Neisseria gonorrhoeae FA 1090
-
-
-
3.1.21.5 Neisseria gonorrhoeae Q5F957 resNgoAXP restriction modification protein
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.72 Ni-NTA agarose column chromatography Neisseria gonorrhoeae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.72 S-adenosyl-L-methionine + DNA adenine the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated Neisseria gonorrhoeae S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?
2.1.1.72 S-adenosyl-L-methionine + DNA adenine the specific sequence recognized by M.NgoAXP is 5'-CCACC-3', in which the adenine residue is methylated Neisseria gonorrhoeae FA 1090 S-adenosyl-L-homocysteine + DNA 6-methyladenine
-
 ?
3.1.21.5 phage lambda DNA + H2O restriction activity requires the presence of both the restriction modification endonuclease protein and the methylase protein of the NgoAXP restriction modification system Neisseria gonorrhoeae ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.72 DNA methyltransferase
-
 Neisseria gonorrhoeae
2.1.1.72 M.NgoAXP
-
 Neisseria gonorrhoeae
2.1.1.72 NgoAXPMod subunit
-
 Neisseria gonorrhoeae
3.1.21.5 type III RM system
-
 Neisseria gonorrhoeae