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Literature summary extracted from

  • Arisaka, M.; Nakamura, T.; Yamada, A.; Negishi, Y.; Aramaki, Y.
    Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells (2010), FEBS Lett., 584, 1016-1020.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.10.1 additional information the activation of PKCdelta is strongly related to the glycosaminoglycans, especially chondroitin sulfate on the plasma membrane Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.1 rottlerin specific inhibitor of PKCdelta Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.10.1 nucleus
-
 Mus musculus 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.10.1 80000
-
 full-length enzyme, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine Mus musculus
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.10.1 phosphoprotein PKCd eltais activated by phosphorylation of a tyrosine residue in the catalytic domain and a threonine residue in the regulatory domain Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 RAW-264.7 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.1 ATP + a [protein]-L-tyrosine
-
 Mus musculus ADP + a [protein]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 PKCdelta
-
 Mus musculus
2.7.10.1 protein kinase Cdelta
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.10.1 ATP
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.7.10.1 physiological function PKCeltad is strongly associated with apoptosis induced by stearylamine-liposomes Mus musculus