Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Hozumi, Y.; Fukaya, M.; Adachi, N.; Saito, N.; Otani, K.; Kondo, H.; Watanabe, M.; Goto, K.
    Diacylglycerol kinase beta accumulates on the perisynaptic site of medium spiny neurons in the striatum (2008), Eur. J. Neurosci., 28, 2409-2422.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.107 cytoplasm localized in the narrow cytoplasmic space between smooth endoplasmic reticulum and plasma membrane Rattus norvegicus 5737
-
2.7.1.107 plasma membrane
-
 Rattus norvegicus 5886
-
2.7.1.107 smooth endoplasmic reticulum
-
 Rattus norvegicus 5790
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.107 90000
-
 isoform DGKbeta, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.107 Rattus norvegicus P49621
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.107 hippocampus moderate labeling in the hippocampus Rattus norvegicus
-
2.7.1.107 medium spiny neuron DGKbeta is expressed in medium spiny neurons constituting the striatonigral and striatopallidal pathways, whereas striatal interneurons are below the detection threshold Rattus norvegicus
-
2.7.1.107 neocortex weak labeling in the neocortex Rattus norvegicus
-
2.7.1.107 olfactory bulb weak labeling in the olfactory bulb Rattus norvegicus
-
2.7.1.107 striatum diacylglycerol kinase beta accumulates on the perisynaptic site of medium spiny neurons in the striatum Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.107 ATP + 1,2-diacylglycerol
-
 Rattus norvegicus ADP + 1,2-diacyl-sn-glycerol 3-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.107 DGKbeta
-
 Rattus norvegicus
2.7.1.107 diacylglycerol kinase beta
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.107 ATP
-
 Rattus norvegicus

General Information

EC Number General Information Comment Organism
2.7.1.107 physiological function isoform DGKbeta is provided to perisynaptic sites of medium spiny neurons so that it can effectively produce 1,2-diacyl-sn-glycerol 3-phosphate upon activation of Gq protein-coupled receptors and modulate the cellular state of striatal output neurons Rattus norvegicus