Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Senatori, O.; Setini, A.; Scirocco, A.; Nicotra, A.
    Effect of short-time exposures to nickel and lead on brain monoamine oxidase from Danio rerio and Poecilia reticulata (2009), Environ. Toxicol., 24, 309-313.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 Clorgyline complete inhibition at 0.01 mM Danio rerio
1.4.3.4 Clorgyline complete inhibition at 0.01 mM Poecilia reticulata
1.4.3.4 Deprenyl complete inhibition at 0.01 mM Danio rerio
1.4.3.4 Deprenyl complete inhibition at 0.01 mM Poecilia reticulata

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Danio rerio Q6NSN2
-
-
1.4.3.4 Poecilia reticulata Q0PGS2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 brain
-
 Danio rerio
-
1.4.3.4 brain
-
 Poecilia reticulata
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.4 0.162
-
 brain enzyme Poecilia reticulata
1.4.3.4 0.243
-
 brain enzyme Danio rerio

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 tyramine + H2O + O2
-
 Danio rerio (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 tyramine + H2O + O2
-
 Poecilia reticulata (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO
-
 Danio rerio
1.4.3.4 MAO
-
 Poecilia reticulata

Expression

EC Number Organism Comment Expression
1.4.3.4 Danio rerio Ni2+ and Pb2+ reduce the expression of MAO in brain after exposure over 24 h and 72 h, overview down
1.4.3.4 Poecilia reticulata Ni2+ and Pb2+ induce the expression of MAO in brain after exposure over 24 h, but the expression level is normalized after 72 h, overview up