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Literature summary extracted from

  • Rai, R.; Wong, C.C.; Xu, T.; Leu, N.A.; Dong, D.W.; Guo, C.; McLaughlin, K.J.; Yates, J.R.; Kashina, A.
    Arginyltransferase regulates alpha cardiac actin function, myofibril formation and contractility during heart development (2008), Development, 135, 3881-3889.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.2.8 a targeting vector is constructed to generate Ate1-deficient mice Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.8 myofibril
-
 Mus musculus 30016
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.8 L-arginyl-tRNAArg + protein Mus musculus
-
 tRNAArg + L-arginyl-[protein]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.8 Mus musculus Q9Z2A5
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.8 cardiac myocyte
-
 Mus musculus
-
2.3.2.8 heart
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.8 L-arginyl-tRNAArg + alpha cardiac actin
-
 Mus musculus tRNAArg + L-arginyl-[alpha cardiac actin]
-
 ?
2.3.2.8 L-arginyl-tRNAArg + protein
-
 Mus musculus tRNAArg + L-arginyl-[protein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.2.8 arginyltransferase
-
 Mus musculus
2.3.2.8 Ate1
-
 Mus musculus

General Information

EC Number General Information Comment Organism
2.3.2.8 physiological function posttranslational arginylation mediated by Ate1 is essential for cardiovascular development and angiogenesis and directly affects the myocardium structure in the developing heart Mus musculus