BRENDA - Enzyme Database

Structure, expression, and regulation of UDP-GlcNAc: dolichol phosphate GlcNAc-1-phosphate transferase (DPAGT1)

Bretthauer, R.K.; Curr. Drug Targets 10, 477-482 (2009)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
2.7.8.15
-
Cricetulus griseus
2.7.8.15
-
Mus musculus
2.7.8.15
-
Rattus norvegicus
2.7.8.15
for expression in Saccharomyces cerevisiae
Bos taurus
2.7.8.15
for expression in Saccharomyces cerevisiae
Homo sapiens
Engineering
EC Number
Amino acid exchange
Commentary
Organism
2.7.8.15
R303K
catalytically inactive mutant
Cricetulus griseus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.15
tunicamycin
-
Bos taurus
2.7.8.15
tunicamycin
-
Cricetulus griseus
2.7.8.15
tunicamycin
-
Homo sapiens
2.7.8.15
tunicamycin
-
Mus musculus
2.7.8.15
tunicamycin
-
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.8.15
membrane
-
Cricetulus griseus
16020
-
2.7.8.15
membrane
-
Mus musculus
16020
-
2.7.8.15
microsome
-
Rattus norvegicus
-
-
2.7.8.15
rough endoplasmic reticulum
-
Cricetulus griseus
5791
-
2.7.8.15
rough endoplasmic reticulum
-
Mus musculus
5791
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.8.15
34000
-
monomer, determined by SDS-PAGE and Western blot analysis
Cricetulus griseus
2.7.8.15
44700
-
-
Homo sapiens
2.7.8.15
46000
-
determined by SDS-PAGE and Western Blot analysis
Bos taurus
2.7.8.15
46470
-
theoretical
Mus musculus
2.7.8.15
50000
-
determined by SDS-PAGE and Western Blot analysis
Bos taurus
2.7.8.15
67000
-
assumed to be a dimeric form, determined by SDS-PAGE and Western blot analysis
Cricetulus griseus
2.7.8.15
70000
-
suggested to be a biological precursor or the degraded native enzyme, determined by SDS-PAGE and Western blot analysis
Bos taurus
2.7.8.15
79400
-
-
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Cricetulus griseus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Mus musculus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Homo sapiens
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Rattus norvegicus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Bos taurus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.8.15
Bos taurus
-
-
-
2.7.8.15
Cricetulus griseus
-
-
-
2.7.8.15
Homo sapiens
-
-
-
2.7.8.15
Mus musculus
-
-
-
2.7.8.15
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
2.7.8.15
-
Bos taurus
2.7.8.15
-
Cricetulus griseus
2.7.8.15
-
Homo sapiens
2.7.8.15
-
Mus musculus
2.7.8.15
-
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.15
CHO cell
-
Cricetulus griseus
-
2.7.8.15
lung
-
Homo sapiens
-
2.7.8.15
lung
-
Rattus norvegicus
-
2.7.8.15
mammary gland
-
Bos taurus
-
2.7.8.15
mammary gland
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Cricetulus griseus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Mus musculus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Homo sapiens
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Rattus norvegicus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Bos taurus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.8.15
-
Cricetulus griseus
2.7.8.15
-
Mus musculus
2.7.8.15
-
Rattus norvegicus
2.7.8.15
for expression in Saccharomyces cerevisiae
Bos taurus
2.7.8.15
for expression in Saccharomyces cerevisiae
Homo sapiens
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
2.7.8.15
R303K
catalytically inactive mutant
Cricetulus griseus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.15
tunicamycin
-
Bos taurus
2.7.8.15
tunicamycin
-
Cricetulus griseus
2.7.8.15
tunicamycin
-
Homo sapiens
2.7.8.15
tunicamycin
-
Mus musculus
2.7.8.15
tunicamycin
-
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.8.15
membrane
-
Cricetulus griseus
16020
-
2.7.8.15
membrane
-
Mus musculus
16020
-
2.7.8.15
microsome
-
Rattus norvegicus
-
-
2.7.8.15
rough endoplasmic reticulum
-
Cricetulus griseus
5791
-
2.7.8.15
rough endoplasmic reticulum
-
Mus musculus
5791
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.8.15
34000
-
monomer, determined by SDS-PAGE and Western blot analysis
Cricetulus griseus
2.7.8.15
44700
-
-
Homo sapiens
2.7.8.15
46000
-
determined by SDS-PAGE and Western Blot analysis
Bos taurus
2.7.8.15
46470
-
theoretical
Mus musculus
2.7.8.15
50000
-
determined by SDS-PAGE and Western Blot analysis
Bos taurus
2.7.8.15
67000
-
assumed to be a dimeric form, determined by SDS-PAGE and Western blot analysis
Cricetulus griseus
2.7.8.15
70000
-
suggested to be a biological precursor or the degraded native enzyme, determined by SDS-PAGE and Western blot analysis
Bos taurus
2.7.8.15
79400
-
-
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Cricetulus griseus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Mus musculus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Homo sapiens
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Rattus norvegicus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
Bos taurus
-
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.8.15
-
Bos taurus
2.7.8.15
-
Cricetulus griseus
2.7.8.15
-
Homo sapiens
2.7.8.15
-
Mus musculus
2.7.8.15
-
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.15
CHO cell
-
Cricetulus griseus
-
2.7.8.15
lung
-
Homo sapiens
-
2.7.8.15
lung
-
Rattus norvegicus
-
2.7.8.15
mammary gland
-
Bos taurus
-
2.7.8.15
mammary gland
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Cricetulus griseus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Mus musculus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Homo sapiens
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Rattus norvegicus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
2.7.8.15
UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
703322
Bos taurus
UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Bos taurus
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Cricetulus griseus
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Homo sapiens
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Mus musculus
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Rattus norvegicus
General Information (protein specific)
EC Number
General Information
Commentary
Organism
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Bos taurus
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Cricetulus griseus
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Homo sapiens
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Mus musculus
2.7.8.15
physiological function
GPT is involved in glycosylation of proteins on asparagine amino acids
Rattus norvegicus