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Literature summary extracted from

  • Richardson, K.L.; Gold-Bouchot, G.; Schlenk, D.
    The characterization of cytosolic glutathione transferase from four species of sea turtles: Loggerhead (Caretta caretta), green (Chelonia mydas), olive ridley (Lepidochelys olivacea), and hawksbill (Eretmochelys imbricata) (2009), Comp. Biochem. Physiol. C, 150, 279-284.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.18 0.122
-
 glutathione pH 7.2, 25°C Eretmochelys imbricata
2.5.1.18 0.163
-
 glutathione pH 7.2, 25°C Chelonia mydas
2.5.1.18 0.172
-
 glutathione pH 7.2, 25°C Caretta caretta
2.5.1.18 0.225
-
 glutathione pH 7.2, 25°C Lepidochelys olivacea
2.5.1.18 0.269
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Caretta caretta
2.5.1.18 0.373
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Lepidochelys olivacea
2.5.1.18 0.455
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Eretmochelys imbricata
2.5.1.18 0.547
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Chelonia mydas

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.18 cytosol
-
 Caretta caretta 5829
-
2.5.1.18 cytosol
-
 Chelonia mydas 5829
-
2.5.1.18 cytosol
-
 Lepidochelys olivacea 5829
-
2.5.1.18 cytosol
-
 Eretmochelys imbricata 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.18 Caretta caretta
-
-
-
2.5.1.18 Chelonia mydas
-
-
-
2.5.1.18 Eretmochelys imbricata
-
-
-
2.5.1.18 Lepidochelys olivacea
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.18 liver
-
 Caretta caretta
-
2.5.1.18 liver
-
 Chelonia mydas
-
2.5.1.18 liver
-
 Lepidochelys olivacea
-
2.5.1.18 liver
-
 Eretmochelys imbricata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.18 4-nitrobenzyl chloride + glutathione
-
 Caretta caretta S-(4-nitrobenzyl)glutathione + HCl
-
 ?
2.5.1.18 4-nitrobenzyl chloride + glutathione
-
 Chelonia mydas S-(4-nitrobenzyl)glutathione + HCl
-
 ?
2.5.1.18 4-nitrobenzyl chloride + glutathione
-
 Lepidochelys olivacea S-(4-nitrobenzyl)glutathione + HCl
-
 ?
2.5.1.18 4-nitrobenzyl chloride + glutathione
-
 Eretmochelys imbricata S-(4-nitrobenzyl)glutathione + HCl
-
 ?
2.5.1.18 DELTA5-androstene-3,17-dione + glutathione
-
 Caretta caretta ?
-
 ?
2.5.1.18 DELTA5-androstene-3,17-dione + glutathione
-
 Chelonia mydas ?
-
 ?
2.5.1.18 DELTA5-androstene-3,17-dione + glutathione
-
 Lepidochelys olivacea ?
-
 ?
2.5.1.18 DELTA5-androstene-3,17-dione + glutathione
-
 Eretmochelys imbricata ?
-
 ?
2.5.1.18 ethacrynic acid + glutathione
-
 Caretta caretta ?
-
 ?
2.5.1.18 ethacrynic acid + glutathione
-
 Chelonia mydas ?
-
 ?
2.5.1.18 ethacrynic acid + glutathione
-
 Lepidochelys olivacea ?
-
 ?
2.5.1.18 ethacrynic acid + glutathione
-
 Eretmochelys imbricata ?
-
 ?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Caretta caretta S-(2,4-dinitrophenyl)glutathione + HCl
-
 ?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Chelonia mydas S-(2,4-dinitrophenyl)glutathione + HCl
-
 ?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Lepidochelys olivacea S-(2,4-dinitrophenyl)glutathione + HCl
-
 ?
2.5.1.18 glutathione + 1-chloro-2,4-dinitrobenzene
-
 Eretmochelys imbricata S-(2,4-dinitrophenyl)glutathione + HCl
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.5.1.18 25
-
 assay at Caretta caretta
2.5.1.18 25
-
 assay at Chelonia mydas
2.5.1.18 25
-
 assay at Lepidochelys olivacea
2.5.1.18 25
-
 assay at Eretmochelys imbricata

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.18 7.2
-
 assay at Caretta caretta
2.5.1.18 7.2
-
 assay at Chelonia mydas
2.5.1.18 7.2
-
 assay at Lepidochelys olivacea
2.5.1.18 7.2
-
 assay at Eretmochelys imbricata

kcat/KM [mM/s]

EC Number kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
2.5.1.18 2.02
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Eretmochelys imbricata
2.5.1.18 3.24
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Chelonia mydas
2.5.1.18 4.16
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Lepidochelys olivacea
2.5.1.18 4.68
-
 glutathione pH 7.2, 25°C Lepidochelys olivacea
2.5.1.18 5.72
-
 1-chloro-2,4-dinitrobenzene pH 7.2, 25°C Caretta caretta
2.5.1.18 6.16
-
 glutathione pH 7.2, 25°C Eretmochelys imbricata
2.5.1.18 7.52
-
 glutathione pH 7.2, 25°C Caretta caretta
2.5.1.18 7.7
-
 glutathione pH 7.2, 25°C Chelonia mydas