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Literature summary extracted from

  • Lavarias, S.; Pasquevich, M.Y.; Dreon, M.S.; Heras, H.
    Partial characterization of a malonyl-CoA-sensitive carnitine O-palmitoyltransferase I from Macrobrachium borellii (Crustacea: Palaemonidae) (2009), Comp. Biochem. Physiol. B, 152, 364-369.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 malonyl-CoA
-
 Macrobrachium borellii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 0.0989
-
 palmitoyl-CoA
-
 Macrobrachium borellii
2.3.1.21 2.18
-
 L-carnitine
-
 Macrobrachium borellii

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrion
-
 Macrobrachium borellii 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 66000
-
 x * 66000, SDS-PAGE, Western blot analysis Macrobrachium borellii

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Macrobrachium borellii
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 midgut gland
-
 Macrobrachium borellii
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.21 0.0367
-
 mitochondrial fraction, 1 mM palmitoyl-CoA Macrobrachium borellii
2.3.1.21 0.0565
-
 mitochondrial fraction Macrobrachium borellii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 L-carnitine + palmitoyl-CoA
-
 Macrobrachium borellii L-palmitoylcarnitine + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.21 ? x * 66000, SDS-PAGE, Western blot analysis Macrobrachium borellii

Synonyms

EC Number Synonyms Comment Organism
2.3.1.21 carnitine O-palmitoyltransferase I
-
 Macrobrachium borellii

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.21 34
-
-
 Macrobrachium borellii

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.21 8
-
-
 Macrobrachium borellii

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.3.1.21 Macrobrachium borellii two-dimensional electrophoresis
-
 5.1

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.3.1.21 0.0252
-
 10 min pre-incubation with malonyl-CoA Macrobrachium borellii malonyl-CoA
2.3.1.21 0.1058
-
 without pre-incubation with malonyl-CoA Macrobrachium borellii malonyl-CoA