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Literature summary extracted from

  • Prodan-Zitnik, I.; Karas-Kuzelicki, N.; Lukac-Bajalo, J.
    Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4-epimerase (GALE) activities (2009), Clin. Biochem., 42, 1561-1564.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.1.3.2 UDP-alpha-D-glucose Homo sapiens
-
 UDP-alpha-D-galactose
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.12 Homo sapiens
-
-
-
5.1.3.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.12 erythrocyte
-
 Homo sapiens
-
5.1.3.2 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.12 UDP-glucose + D-galactose 1-phosphate
-
 Homo sapiens D-glucose 1-phosphate + UDP-galactose
-
 ?
5.1.3.2 UDP-alpha-D-glucose
-
 Homo sapiens UDP-alpha-D-galactose
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.7.7.12 galactose-1-phosphate uridyltransferase
-
 Homo sapiens
5.1.3.2 GalE
-
 Homo sapiens
5.1.3.2 UDP-galactose-4'-epimerase
-
 Homo sapiens
5.1.3.2 UDP-galactose-4-epimerase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
5.1.3.2 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.1.3.2 9.5
-
 assay at Homo sapiens

General Information

EC Number General Information Comment Organism
5.1.3.2 malfunction GALE deficiency leads to mild or severe disease with clinical symptoms similar to classical galactosemia Homo sapiens
5.1.3.2 metabolism GALE catalyzes the third step of the Leloir pathway of galactose metabolism Homo sapiens