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Literature summary extracted from

  • Delaby, C.; Lyoumi, S.; Ducamp, S.; Martin-Schmitt, C.; Gouya, L.; Deybach, J.C.; Beaumont, C.; Puy, H.
    Excessive erythrocyte PPIX influences the hematologic status and iron metabolism in patients with dominant erythropoietic protoporphyria (2009), Cell. Mol. Biol. (Noisy-le-grand), 55, 45-52.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.98.1.1 diagnostics partial defiency of the last enzyme of the heme biosynthetic pathway (namely ferrochelatase) in humans is responsible for erythropoietic protoporphyria Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.98.1.1 protoporphyrin + Fe2+ Homo sapiens
-
 protoheme + 2 H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.98.1.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.98.1.1 protoporphyrin + Fe2+
-
 Homo sapiens protoheme + 2 H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.98.1.1 FeCH
-
 Homo sapiens
4.98.1.1 ferrochelatase
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
4.98.1.1 malfunction partial defiency of the last enzyme of the heme biosynthetic pathway (namely ferrochelatase) in humans is responsible for erythropoietic protoporphyria Homo sapiens