Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jang, S.M.; Kim, J.W.; Kim, C.H.; Kim, D.; Rhee, S.; Choi, K.H.
    p19(ras) Represses proliferation of non-small cell lung cancer possibly through interaction with neuron-specific enolase (NSE) (2010), Cancer Lett., 289, 91-98.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.1.11 expressed in Escherichia coli BL21 cells Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.11 p19ras when full-length p19ras and C-terminal region are bound to NSE, it inhibits the enzymatic activity of NSE, p19ras interacts with enolase alpha and represses its enzymatic activity in vitro Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.11 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.11 glutathione-Sepharose 4B bead chromatography, gel filtration Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.11 HEK-293 cell
-
 Homo sapiens
-
4.2.1.11 NCI-H1299 cell
-
 Homo sapiens
-
4.2.1.11 neuron
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.11 2-phospho-D-glycerate
-
 Homo sapiens phosphoenolpyruvate + H2O
-
 r

Synonyms

EC Number Synonyms Comment Organism
4.2.1.11 Eno-alpha
-
 Homo sapiens
4.2.1.11 Eno2
-
 Homo sapiens
4.2.1.11 enolase 2
-
 Homo sapiens
4.2.1.11 enolase alpha
-
 Homo sapiens
4.2.1.11 enolase gamma
-
 Homo sapiens
4.2.1.11 neuron-specific enolase
-
 Homo sapiens
4.2.1.11 NSE
-
 Homo sapiens