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Literature summary extracted from

  • Ray, B.; Simon, J.R.; Lahiri, D.K.
    Determination of high-affinity choline uptake (HACU) and choline acetyltransferase (ChAT) activity in the same population of cultured cells (2009), Brain Res., 1297, 160-168.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.6 acetyl-CoA + choline Homo sapiens formation of acetylcholine in cholinergic neurons largely depends on both the levels of choline being transported into the cells from the extracellular space and the activity of ChAT, kinetics of choline uptake in the SK-N-SH cells CoA + O-acetylcholine acetylcholine is the neurotransmitter used by cholinergic neurons ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.6 cell culture
-
 Homo sapiens
-
2.3.1.6 neuroblastoma cell
-
 Homo sapiens
-
2.3.1.6 neuron cholinergic Homo sapiens
-
2.3.1.6 SK-N-SH cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.6 acetyl-CoA + choline
-
 Homo sapiens CoA + O-acetylcholine
-
 ?
2.3.1.6 acetyl-CoA + choline formation of acetylcholine in cholinergic neurons largely depends on both the levels of choline being transported into the cells from the extracellular space and the activity of ChAT, kinetics of choline uptake in the SK-N-SH cells Homo sapiens CoA + O-acetylcholine acetylcholine is the neurotransmitter used by cholinergic neurons ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.6 ChAT
-
 Homo sapiens
2.3.1.6 choline acetyltransferase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.6 acetyl-CoA
-
 Homo sapiens