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Literature summary extracted from

  • Barla, F.; Higashijima, H.; Funai, S.; Sugimoto, K.; Harada, N.; Yamaji, R.; Fujita, T.; Nakano, Y.; Inui, H.
    Inhibitive effects of alkyl gallates on hyaluronidase and collagenase (2009), Biosci. Biotechnol. Biochem., 73, 2335-2337.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.35 decyl gallate
-
 Bos taurus
3.2.1.35 disodium cromoglycate
-
 Bos taurus
3.2.1.35 heptyl gallate
-
 Bos taurus
3.2.1.35 hexyl gallate
-
 Bos taurus
3.2.1.35 additional information not inhibited by gallic acid, methyl gallate, ethyl gallate, propyl gallate, butyl galate, dodecyl gallate, octyl 3-hydroxybenzoate, and octyl 4-hydroxybenzoate Bos taurus
3.2.1.35 nonyl gallate
-
 Bos taurus
3.2.1.35 octyl 3,4-dihydroxybenzoate
-
 Bos taurus
3.2.1.35 octyl 3,5-dihydroxybenzoate
-
 Bos taurus
3.2.1.35 octyl gallate
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.35 hyaluronan + 2 H2O Bos taurus
-
 N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.35 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.35 testis
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.35 hyaluronan + 2 H2O
-
 Bos taurus N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.35 hyaluronidase
-
 Bos taurus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.2.1.35 0.106
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus octyl gallate
3.2.1.35 0.112
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus heptyl gallate
3.2.1.35 0.113
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus octyl 3,5-dihydroxybenzoate
3.2.1.35 0.167
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus nonyl gallate
3.2.1.35 0.253
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus hexyl gallate
3.2.1.35 0.45
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus disodium cromoglycate
3.2.1.35 0.58
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus decyl gallate
3.2.1.35 0.902
-
 in 0.1 M sodium acetate buffer, pH 4.0, at 37°C Bos taurus octyl 3,4-dihydroxybenzoate