EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.2.9 | 2,3,4,5-tetrabromo-6-(3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid | inhibitor identified by structure-based virtual screening | Escherichia coli | |
6.3.2.10 | 4-[(pentachlorobenzyl)sulfanyl]-6-sulfanyl-1,3,5-triazin-2-ol | i.e. NSC 209931, inhibitor identified by structure-based virtual screening | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.2.9 | Escherichia coli | P14900 | - |
- |
6.3.2.10 | Escherichia coli | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.9 | ATP + UDP-N-acetylmuramate-L-alanine + D-glutamate | - |
Escherichia coli | ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate | - |
? | |
6.3.2.10 | ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-diaminopimelic acid + D-alanyl-D-alanine | - |
Escherichia coli | ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-diaminopimeloyl-D-alanyl-D-alanine | - |
? |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
6.3.2.9 | 0.01 | - |
pH 8.0, 37°C | Escherichia coli | 2,3,4,5-tetrabromo-6-(3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid | |
6.3.2.10 | 0.063 | - |
pH 8.0, 37°C | Escherichia coli | 4-[(pentachlorobenzyl)sulfanyl]-6-sulfanyl-1,3,5-triazin-2-ol |