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Literature summary extracted from

  • Dullaart, R.P.; Perton, F.; Kappelle, P.J.; de Vries, R.; Sluiter, W.J.; van Tol, A.
    Plasma lecithin: cholesterol acyltransferase activity modifies the inverse relationship of C-reactive protein with HDL cholesterol in nondiabetic men (2010), Biochim. Biophys. Acta, 1801, 84-88.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.43 apolipoprotein A-I
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.43 extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.43 additional information Homo sapiens plasma high-sensitivity C-reactive protein, CRP, is correlated inversely with HDL-C and apo A-I, and positively with LCAT activity, interaction between apo A-I and LCAT activity on CRP, interaction analysis, overview ?
-
 ?
2.3.1.43 phosphatidylcholine + cholesterol Homo sapiens
-
 cholesteryl ester + lysophosphatidylcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
 nondiabetic men without cardiovascular disease
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.43 blood plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.43 additional information
-
 LCAT activity in plasma Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 additional information plasma high-sensitivity C-reactive protein, CRP, is correlated inversely with HDL-C and apo A-I, and positively with LCAT activity, interaction between apo A-I and LCAT activity on CRP, interaction analysis, overview Homo sapiens ?
-
 ?
2.3.1.43 phosphatidylcholine + cholesterol
-
 Homo sapiens cholesteryl ester + lysophosphatidylcholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.43 LCAT
-
 Homo sapiens
2.3.1.43 lecithin:cholesterol acyltransferase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.43 37
-
 assay at Homo sapiens