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Literature summary extracted from

  • Coaxum, S.D.; Garnovskaya, M.N.; Gooz, M.; Baldys, A.; Raymond, J.R.
    Epidermal growth factor activates Na(+/)H(+) exchanger in podocytes through a mechanism that involves Janus kinase and calmodulin (2009), Biochim. Biophys. Acta, 1793, 1174-1181.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.10.2 Epidermal growth factor epidermal growth factor increases levels of tyrosine phosphorylation of Jak2 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.2 renal glomerular podocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.2 ATP + a [protein]-L-tyrosine
-
 Homo sapiens ADP + a [protein]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.2 JAK2
-
 Homo sapiens
2.7.10.2 Janus kinase 2
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.10.2 ATP
-
 Homo sapiens